Polyamine distribution in eukaryotes: occurrence of sym-nor-spermidine and sym-nor-spermine in arthropods
نویسندگان
چکیده
منابع مشابه
sym-Homospermidine, a naturally occurring polyamine.
1,9-Diamino-5-azanonane (1, H2N(CH2)4NH(CH2)4NH2), symmetrical “homospermidine,” previously unreported in nature, has now been discovered in sandal (Santalum album L.), where it comprises 0.5-1.5% of the weight of the dried leaves. The new polyamine is conveniently isolated from an aqueous extract of the leaves by ion-exchange 1^) uring a routine examination of the amino acids from an ethanolic...
متن کاملPolyamine-dependent regulation of spermidine-spermine N1-acetyltransferase mRNA translation.
Spermidine-spermine N(1)-acetyltransferase (SSAT) is induced in response to an elevation in intracellular polyamine pools. The increased enzyme activity is the result of an increase in gene transcription, mRNA translation, and protein stability. Induction of SSAT by polyamine analogues can lead to intracellular polyamine depletion and apoptosis. The mechanism by which polyamines alter the trans...
متن کاملConsequences of Spermine Synthase or Spermidine/Spermine N- Acetyltransferase Deficiency in Polyamine Metabolism
A vast number of studies have linked polyamines to numerous cellular functions but less is known about the possible physiological functions of the individual polyamines. The specific gene targeting technique has provided a new potential way to resolve this mystery. We generated two separate embryonic stem (ES) cell lines where either spermine synthase gene (SPMSy) or spermidine/spermine N-acety...
متن کاملPolyamine-regulated translation of spermidine/spermine-N1-acetyltransferase.
Rapid synthesis of the polyamine catabolic enzyme spermidine/spermine-N(1)-acetyltransferase (SSAT) in response to increased polyamines is an important polyamine homeostatic mechanism. Indirect evidence has suggested that there is an important control mechanism involving the release of a translational repressor protein that allows the immediate initiation of SSAT protein synthesis without RNA t...
متن کاملSYM and Fermion Droplets
The matrix models which are conjectured to compute the circle Wilson loop and its correlator with chiral primary operators are mapped onto normal matrix models. A fermion droplet picture analogous to the well-known one for chiral primary operators is shown to emerge in the large N limit. Several examples are computed. We find an interesting selection rule for the correlator of a single trace Wi...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1978
ISSN: 0014-5793
DOI: 10.1016/0014-5793(78)80928-4